Alexandre Bossu

Comparison of pharmacological activity of macitentan and bosentan in preclinical models of systemic and pulmonary hypertension

Marc Iglarz, Alexandre Bossu, Daniel Wanner et al. · Life Sciences · 2014 · 43 citations · Full text

Torsade de pointes arrhythmias arise at the site of maximal heterogeneity of repolarization in the chronic complete atrioventricular block dog

Albert Dunnink, Thom R.G. Stams, Alexandre Bossu et al. · EP Europace · 2016 · 42 citations · Full text

Short-Lasting Episodes of Torsade de Pointes in the Chronic Atrioventricular Block Dog Model Have a Focal Mechanism, While Longer-Lasting Episodes Are Maintained by Re-Entry

Nele Vandersickel, Alexandre Bossu, Jan De Neve et al. · JACC. Clinical electrophysiology · 2017 · 38 citations · Full text

Focal Mechanism, Electrophysiological Evaluation, Short-lasting Episodes +7

Selective late sodium current inhibitor GS‐458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia

Alexandre Bossu, Marien J. C. Houtman, Veronique M.F. Meijborg et al. · British Journal of Pharmacology · 2018 · 38 citations · Full text

The inward rectifier current inhibitor PA‐6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models

Yuan Ji, Rosanne Varkevisser, Dragan Opačić et al. · British Journal of Pharmacology · 2017 · 30 citations · Full text