Nataraj Jagadeesan

Biologic TNF-α inhibitors reduce microgliosis, neuronal loss, and tau phosphorylation in a transgenic mouse model of tauopathy

Weijun Ou, Joshua Yang, Juste Simanauskaite et al. · Journal of Neuroinflammation · 2021 · 109 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Efficacy and Safety of a Brain-Penetrant Biologic TNF-α Inhibitor in Aged APP/PS1 Mice

Weijun Ou, Yuu Ohno, Joshua Yang et al. · Pharmaceutics · 2022 · 45 citations · Full text

Pharmacy, Neurology, Pharmacology +17

Adhesion Molecule L1 Agonist Mimetics Protect Against the Pesticide Paraquat-Induced Locomotor Deficits and Biochemical Alterations in Zebrafish

Thomson Patrick Joseph, Nataraj Jagadeesan, Liu Sai et al. · Frontiers in Neuroscience · 2020 · 20 citations · Full text

Pharmacy, Neuroscience, Pharmacology +17

Hepatic LRP-1 plays an important role in amyloidosis in Alzheimer's disease mice: Potential role in chronic heavy alcohol feeding

Devaraj V. Chandrashekar, G. Chuli Roules, Nataraj Jagadeesan et al. · Neurobiology of Disease · 2024 · 19 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Modulation of hippocampal protein expression by a brain penetrant biologic TNF-α inhibitor in the 3xTg Alzheimer’s disease mice

Nataraj Jagadeesan, G. Chuli Roules, Devaraj V. Chandrashekar et al. · Journal of Translational Medicine · 2024 · 15 citations · Full text

Medicine, Neuroscience, Pharmacology +17