Brian Buckley

Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase

Fangliang Zhang, Devang M. Patel, Kristen Colavita et al. · Nature Communications · 2015 · 50 citations · Full text

Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448)

David E. Heppner, Florian Wittlinger, Tyler S. Beyett et al. · ACS Medicinal Chemistry Letters · 2022 · 49 citations · Full text

Lazertinib Inhibition, Molecular Biology, Chemical Biology +16

Small molecule inhibitors of arginyltransferase regulate arginylation-dependent protein degradation, cell motility, and angiogenesis

Sougata Saha, Junling Wang, Brian Buckley et al. · Biochemical Pharmacology · 2012 · 44 citations · Full text

Small Molecule Inhibitors, Signal Transduction, Angiogenesis +9

Targeting RING domains of Mdm2–MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells

Wenjie Wu, Chao Xu, Xing Ling et al. · Cell Death and Disease · 2015 · 39 citations · Full text

NTRK1 is a positive regulator of YAP oncogenic function

Xinyuan Yang, He Shen, Brian Buckley et al. · Oncogene · 2018 · 26 citations · Full text

Signal Transduction, Signaling Pathway, Genetics +5