miR-222 Is Necessary for Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling

Xiaojun Liu, Junjie Xiao, Han Zhu, +10

Cell Metabolism

Cardiac MuscleCardiomyopathyCardiac ReprogrammingExercise-induced Cardiac GrowthCardiovascular Disease +11

Integrating Cardiac PIP3 and cAMP Signaling through a PKA Anchoring Function of p110γ

Alessia Perino, Alessandra Ghigo, Enrico Ferrero, +20

Molecular Cell

Cardiac MuscleMolecular PhysiologySignal TransductionSignaling PathwayCamp Signaling +12

PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling

Laura Braccini, Elisa Ciraolo, Carlo Cosimo Campa, +13

Nature Communications

Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications

Cécile Vernochet, Federico Damilano, Arnaud Mourier, +6

The FASEB Journal

Activin type II receptor signaling in cardiac aging and heart failure

Jason D. Roh, Ryan Hobson, Vinita Chaudhari, +19

Science Translational Medicine

Phosphoinositide 3-Kinase γ Protects Against Catecholamine-Induced Ventricular Arrhythmia Through Protein Kinase A–Mediated Regulation of Distinct Phosphodiesterases

Alessandra Ghigo, Alessia Perino, Hind Mehel, +17

Circulation

Involvement of Phosphoinositide 3-Kinase γ in Angiogenesis and Healing of Experimental Myocardial Infarction in Mice

Mauro Siragusa, Rajesh Katare, Marco Meloni, +4

Circulation Research

Exercise training reverses cardiac aging phenotypes associated with heart failure with preserved ejection fraction in male mice

Jason D. Roh, Nicholas Houstis, Andy Yu, +14

Aging Cell

Phosphoinositide 3-Kinase γ Gene Knockout Impairs Postischemic Neovascularization and Endothelial Progenitor Cell Functions

Paolo Madeddu, N Kraenkel, Lucíola S. Barcelos, +11

Arteriosclerosis Thrombosis and Vascular Biology

Distinct Effects of Leukocyte and Cardiac Phosphoinositide 3-Kinase γ Activity in Pressure Overload–Induced Cardiac Failure

Federico Damilano, Irene Franco, Cinzia Perrino, +9

Circulation