L Greenberger

Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes.

Keisuke Miyake, Lyn A. Mickley, Thomas Litman et al. · PubMed · 1999 · 822 citations · Full text

Medicine, Molecular Biology, Oncology +14

Multiple mechanisms confer drug resistance to mitoxantrone in the human 8226 myeloma cell line.

Lori Hazlehurst, Nils E. Foley, Mary Gleason-Guzman et al. · PubMed · 1999 · 115 citations

Medicine, Oncology, Pharmacology +14

The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification.

ML Slovak, J. Pelkey Ho, Susan P.C. Cole et al. · PubMed · 1995 · 101 citations

Medicine, Molecular Biology, Molecular Genetics +12