The Apelin-APJ Axis Is an Endogenous Counterinjury Mechanism in Experimental Acute Lung Injury

Xiaofang Fan, Feng Xue, Yueqi Zhang, +6

CHEST Journal

AsthmaInflammationAcute Lung InjuryPulmonary CirculationInflammatory Lung Disease +11

Intermedin modulates hypoxic pulmonary vascular remodeling by inhibiting pulmonary artery smooth muscle cell proliferation

Sun‐Zhong Mao, Xiaofang Fan, Feng Xue, +6

Pulmonary Pharmacology & Therapeutics

InflammationPulmonary Arterial HypertensionPulmonary CirculationPhysiologyPulmonary Physiology +5

Selective inhibition of endothelial NF-κB signaling attenuates chronic intermittent hypoxia-induced atherosclerosis in mice

Dongmei Song, Guoqiang Fang, Sun‐Zhong Mao, +5

Atherosclerosis

InflammationSelective InhibitionCardiovascular DiseaseMedicineVascular Pharmacology +10

SIRT1 Mediates Apelin-13 in Ameliorating Chronic Normobaric Hypoxia-induced Anxiety-like Behavior by Suppressing NF-κB Pathway in Mice Hippocampus

Junming Fan, Hui Guang, Haizeng Zhang, +9

Neuroscience

PsychoneuroimmunologyStress HormoneBehavioral NeuroscienceSirt1 Mediates Apelin-13Immunology +6

Chronic Intermittent Hypoxia Exposure Induces Atherosclerosis in ApoE Knockout Mice

Guoqiang Fang, Dongmei Song, Xiaobing Ye, +3

American Journal Of Pathology

InflammationMetabolic SyndromeVascular DiseaseCardiovascular DiseaseLipid Peroxidation +9

Chronic intermittent hypoxia induces atherosclerosis by NF-κB-dependent mechanisms

Dagang Song, Guoqiang Fang, Sun‐Zhong Mao, +4

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

InflammationMetabolic SyndromeCardiovascular DiseasePhysiologyImmunology +10

Upregulation of miR-335-3p by NF-κB Transcriptional Regulation Contributes to the Induction of Pulmonary Arterial Hypertension via APJ during Hypoxia

Junming Fan, Xiaofang Fan, Hui Guang, +14

International Journal of Biological Sciences

YAP activity protects against endotoxemic acute lung injury by activating multiple mechanisms

Lingyan Liu, Xiaoqiong Shan, Fukun Zhang, +6

International Journal of Molecular Medicine

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationMultiple MechanismsImmunology +19

Amelioration of apelin-13 in chronic normobaric hypoxia-induced anxiety-like behavior is associated with an inhibition of NF-κB in the hippocampus

Junming Fan, Lu Ding, Dongmei Xia, +11

Brain Research Bulletin

PsychoneuroimmunologyBehavioral NeuroscienceMedicineAffective NeurosciencePsychopharmacology +5

YAP promotes endothelial barrier repair by repressing STAT3/VEGF signaling

Xiaofang Fan, Xiaoqiong Shan, Shan Jiang, +10

Life Sciences

Endothelial Cell PathobiologyDevelopmental BiologyAngiogenesisSignal TransductionEndothelial Dysfunction +6