Mengdi Shang

Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones

Yingqian Zhang, Chuanlong Zang, Guo‐Ce An et al. · Nature Communications · 2020 · 84 citations · Full text

Life Sciences, Biochemistry, Biotechnology +14

A light-responsive, self-immolative linker for controlled drug delivery <i>via</i> peptide- and protein-drug conjugates

Chuanlong Zang, Huawei Wang, Tiantian Li et al. · Chemical Science · 2019 · 44 citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +16

Dual antisense oligonucleotide targeting miR-21/miR-155 synergize photodynamic therapy to treat triple-negative breast cancer and inhibit metastasis

Mengdi Shang, Yiyang Wu, Yeyang Wang et al. · Biomedicine & Pharmacotherapy · 2021 · 42 citations · Full text

Medicine, Oncology, Pharmacology +17

Histones participate in base excision repair of 8-oxodGuo by transiently cross-linking with active repair intermediates in nucleosome core particles

Mengtian Ren, Mengdi Shang, Huawei Wang et al. · Nucleic Acids Research · 2020 · 32 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Cellular uptake of extracellular nucleosomes induces innate immune responses by binding and activating cGMP-AMP synthase (cGAS)

Huawei Wang, Chuanlong Zang, Mengtian Ren et al. · Scientific Reports · 2020 · 27 citations · Full text

Life Sciences, Immunology, Molecular Biology +13