Rebecca W. Powell

Gene Array and Fluorescence <i>In situ</i> Hybridization Biomarkers of Activity of Saracatinib (AZD0530), a Src Inhibitor, in a Preclinical Model of Colorectal Cancer

John J. Arcaroli, Basel M. Touban, Aik Choon Tan et al. · Clinical Cancer Research · 2010 · 59 citations · Full text

Common PIK3CA Mutants and a Novel 3′ UTR Mutation Are Associated with Increased Sensitivity to Saracatinib

John J. Arcaroli, Kevin S. Quackenbush, Rebecca W. Powell et al. · Clinical Cancer Research · 2012 · 41 citations · Full text

Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model

John J. Arcaroli, Kevin S. Quackenbush, Alicia Purkey et al. · British Journal of Cancer · 2013 · 37 citations · Full text

ALDH+ tumor‐initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a γ‐secretase inhibitor and irinotecan in colorectal cancer

John J. Arcaroli, Rebecca W. Powell, Marileila Varella‐Garcia et al. · Molecular Oncology · 2012 · 33 citations · Full text

Biomarker‐driven trial in metastatic pancreas cancer: feasibility in a multicenter study of saracatinib, an oral <scp>S</scp>rc inhibitor, in previously treated pancreatic cancer

John J. Arcaroli, Kevin S. Quackenbush, Arvind Dasari et al. · Cancer Medicine · 2012 · 15 citations · Full text