Joost C.M. Uitdehaag

X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the α-amylase family

Joost C.M. Uitdehaag, Renée Mosi, Kor H. Kalk et al. · Nature Structural Biology · 1999 · 389 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

The three transglycosylation reactions catalyzed by cyclodextrin glycosyltransferase from <i>Bacillus circulans</i> (strain 251) proceed via different kinetic mechanisms

Bart A. van der Veen, Gert‐Jan W. M. van Alebeek, Joost C.M. Uitdehaag et al. · European Journal of Biochemistry · 2000 · 181 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

The Cyclization Mechanism of Cyclodextrin Glycosyltransferase (CGTase) as Revealed by a γ-Cyclodextrin-CGTase Complex at 1.8-Å Resolution

Joost C.M. Uitdehaag, Kor H. Kalk, Bart A. van der Veen et al. · Journal of Biological Chemistry · 1999 · 133 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model

Ana Maia, J. de Man, Ute Boon et al. · Annals of Oncology · 2015 · 123 citations

Medicine, Oncology, Pharmacology +14

Engineering of Cyclodextrin Product Specificity and pH Optima of the Thermostable Cyclodextrin Glycosyltransferase from Thermoanaerobacterium thermosulfurigenes EM1

Richèle D. Wind, Joost C.M. Uitdehaag, R.M. Buitelaar et al. · Journal of Biological Chemistry · 1998 · 113 citations · Full text

Life Sciences, Biochemistry, Microbiology +17