Alexander M. Spring

DALI: Defining Antibiotic Levels in Intensive Care Unit Patients: Are Current  -Lactam Antibiotic Doses Sufficient for Critically Ill Patients?

Jason A. Roberts, Sanjoy K. Paul, Murat Akova et al. · Clinical Infectious Diseases · 2014 · 1.1K citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

XIAP impairs Smac release from the mitochondria during apoptosis

Lorna Flanagan, Jordi Sebastià, Liam P. Tuffy et al. · Cell Death and Disease · 2010 · 62 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction

Willem J. de Lange, Adrian C. Grimes, Laura F. Hegge et al. · The Journal of General Physiology · 2013 · 35 citations · Full text

Life Sciences, Cardiology, Genetics +13

Combination Treatment with Sublethal Ionizing Radiation and the Proteasome Inhibitor, Bortezomib, Enhances Death-Receptor Mediated Apoptosis and Anti-Tumor Immune Attack

Ercan Çaçan, Alexander M. Spring, Anita Kumari et al. · International Journal of Molecular Sciences · 2015 · 24 citations · Full text

Life Sciences, Immunology, Oncology +17

DNA Sequence Context Conceals α-Anomeric Lesions

Christopher N. Johnson, Alexander M. Spring, Sunil Desai et al. · Journal of Molecular Biology · 2011 · 23 citations

Life Sciences, Genetics, Molecular Biology +2