Edna C. Hardeman

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

Lars M. Ittner, Yazi D. Ke, Fabien Delerue et al. · Cell · 2010 · 1.8K citations · Full text

Synaptic Plasticity, Neurodegenerative Diseases, Molecular Neuroscience +11

Plasticity of the Differentiated State

Helen M. Blau, Grace K. Pavlath, Edna C. Hardeman et al. · Science · 1985 · 833 citations

Muscle Function, Engineering, Muscle Gene Expression +20

Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans

Daniel G. MacArthur, Jane T. Seto, Joanna M. Raftery et al. · Nature Genetics · 2007 · 325 citations · Full text

Knockout Mouse, Muscle Physiology, Muscle Function +12

An Actn3 knockout mouse provides mechanistic insights into the association between  -actinin-3 deficiency and human athletic performance

Daniel G. MacArthur, Jane T. Seto, Stephen Chan et al. · Human Molecular Genetics · 2008 · 289 citations · Full text

Targeted selection of recombinant clones through gene dosage effects.

Jasper Rine, William Hansen, Edna C. Hardeman et al. · Proceedings of the National Academy of Sciences · 1983 · 261 citations · Full text

Engineering, Cellular Enzymology, Gene Dosage Effects +15