Edwin D. Hawkins

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis

André L. Samson, Ying Zhang, Niall D. Geoghegan et al. · Nature Communications · 2020 · 335 citations · Full text

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

Najoua Lalaoui, Steven E. Boyden, Hirotsugu Oda et al. · Nature · 2019 · 316 citations · Full text

Autoinflammatory Disorders, Pathogenesis, Immunology +9

Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML

Delfim Duarte, Edwin D. Hawkins, Olufolake Akinduro et al. · Cell stem cell · 2017 · 314 citations · Full text

Developmental Biology, Angiogenesis, Medicine +15

Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

Axel Kallies, Edwin D. Hawkins, Gabrielle T. Belz et al. · Nature Immunology · 2006 · 310 citations

Transcriptional Regulation, T Cell Homeostasis, Signal Transduction +11

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

Jonathan B. Baell, David J. Leaver, S.J. Hermans et al. · Nature · 2018 · 300 citations · Full text

Cancer Research, Chromatin, Tumour Growth +12