Toshiki Kino

Mangiferin suppresses CIA by suppressing the expression of TNF-α, IL-6, IL-1β, and RANKL through inhibiting the activation of NF-κB and ERK1/2.

Masanobu Tsubaki, Tomoya Takeda, Toshiki Kino et al. · PubMed · 2015 · 56 citations · Full text

Cia Mice, Immunology, Immune Regulation +22

The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin‐induced apoptosis is mediated via suppression of the Ras/<scp>ERK</scp> and Ras/<scp>mTOR</scp> pathways

Masanobu Tsubaki, Daichiro Fujiwara, Tomoya Takeda et al. · Clinical and Experimental Pharmacology and Physiology · 2017 · 42 citations

Statins improve survival by inhibiting spontaneous metastasis and tumor growth in a mouse melanoma model.

Masanobu Tsubaki, Tomoya Takeda, Toshiki Kino et al. · PubMed · 2015 · 38 citations

Immunology, Cell Proliferation, Cancer Biology +19

Mangiferin induces apoptosis in multiple myeloma cell lines by suppressing the activation of nuclear factor kappa B-inducing kinase

Tomoya Takeda, Masanobu Tsubaki, Toshiki Kino et al. · Chemico-Biological Interactions · 2016 · 35 citations

Nuclear Factor, Medicine, Apoptosis +10

Statins inhibited the MIP-1α expression via inhibition of Ras/ERK and Ras/Akt pathways in myeloma cells

Masanobu Tsubaki, Kenji Mashimo, Tomoya Takeda et al. · Biomedicine & Pharmacotherapy · 2016 · 30 citations

Inflammation, Signal Transduction, Mip-1α Expression +10