Michaela Blech

High-concentration protein formulations: How high is high?

Patrick Garidel, Alexander Kühn, Lars V. Schäfer et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2017 · 175 citations

Medicine, High-concentration Protein Formulations, Protein Engineering +5

Prediction and Reduction of the Aggregation of Monoclonal Antibodies

Rob van der Kant, Anne R. Karow‐Zwick, Joost Van Durme et al. · Journal of Molecular Biology · 2017 · 144 citations · Full text

One Target—Two Different Binding Modes: Structural Insights into Gevokizumab and Canakinumab Interactions to Interleukin-1β

Michaela Blech, Daniel Peter, Peter M. Fischer et al. · Journal of Molecular Biology · 2012 · 96 citations

Inflammation, Cytokine, Molecular Immunology +11

Boosting antibody developability through rational sequence optimization

Daniel Seeliger, Patrick Schulz, Tobias Litzenburger et al. · mAbs · 2015 · 65 citations · Full text

Heuristic Sequence Analysis, Engineering, Rational Sequence Optimization +17

Surface Tension and Self-association Properties of Aqueous Polysorbate 20 HP and 80 HP Solutions: Insights into Protein Stabilisation Mechanisms

Patrick Garidel, Michaela Blech, Julia Buske et al. · Journal of Pharmaceutical Innovation · 2020 · 61 citations

Engineering, Polymer Solution, Hp Solutions +9