Immune-Instructive Polymers Control Macrophage Phenotype and Modulate the Foreign Body Response In Vivo

Hassan M. Rostam, Leanne E. Fisher, Andrew L. Hook, +15

Matter

Mobility and invasiveness of metastatic esophageal cancer are potentiated by shear stress in a ROCK- and Ras-dependent manner

Karen Lawler, Eílis Foran, Gerald C. O’Sullivan, +2

American Journal of Physiology-Cell Physiology

Surgical OncologyEngineeringEsophageal CancerCell AdhesionPathology +23

Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway

Aslihan Ugun‐Klusek, Michael H. Tatham, Jamal Elkharaz, +9

Cell Death and Disease

MitophagyProteasomeCell DeathMolecular BiologyCytoskeleton +18

Shear stress induces internalization of E‐cadherin and invasiveness in metastatic oesophageal cancer cells by a Src‐dependent pathway

Karen Lawler, Gerald C. O’Sullivan, Aideen Long, +1

Cancer Science

Esophageal CancerCell AdhesionCancer BiologyCellular PhysiologyTumor Biology +14

Shear stress modulates the interaction of platelet-secreted matrix proteins with tumor cells through the integrin α_vβ₃

Karen Lawler, Gerardene Meade, Gerald C. O’Sullivan, +1

American Journal of Physiology-Cell Physiology

EngineeringCell AdhesionTumor CellsBiomedical EngineeringCellular Physiology +24

Microparticles Decorated with Cell‐Instructive Surface Chemistries Actively Promote Wound Healing

Arsalan Latif, Leanne E. Fisher, Adam A. Dundas, +9

Advanced Materials

Tissue EngineeringEngineeringBiomaterials DesignBiofabricationBiomedical Engineering +15

Pale Body-Like Inclusion Formation and Neurodegeneration following Depletion of 26S Proteasomes in Mouse Brain Neurones are Independent of α-Synuclein

Simon Paine, Glenn Anderson, Karen Bedford, +4

PLoS ONE

ProteasomeMolecular BiologyNeurochemical BiomarkersSynaptic SignalingSocial Sciences +23

Implications for oxidative stress and astrocytes following 26S proteasomal depletion in mouse forebrain neurones

Jamal Elkharaz, Aslihan Ugun‐Klusek, Dumitru Constantin‐Teodosiu, +5

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

IgM and IgA augmented autoantibody signatures improve early‐stage detection of colorectal cancer prior to nodal and distant spread

M. S. I. Roney, Catharine Lanagan, Yonghua Sheng, +5

Clinical & Translational Immunology

Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons

Philippine C. Geiszler, Aslihan Ugun‐Klusek, Karen Lawler, +6

Scientific Reports