Roy Chun-Laam Ng

Adiponectin suppresses amyloid-β oligomer (AβO)-induced inflammatory response of microglia via AdipoR1-AMPK-NF-κB signaling pathway

Min Jian, Jason Shing-Cheong Kwan, M Bunting et al. · Journal of Neuroinflammation · 2019 · 194 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Chronic adiponectin deficiency leads to Alzheimer’s disease-like cognitive impairments and pathologies through AMPK inactivation and cerebral insulin resistance in aged mice

Roy Chun-Laam Ng, On-Yin Cheng, Min Jian et al. · Molecular Neurodegeneration · 2016 · 186 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer’s disease

Ashok Iyaswamy, Abhimanyu Thakur, Xinjie Guan et al. · Signal Transduction and Targeted Therapy · 2023 · 118 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer’s disease mouse model

Roy Chun-Laam Ng, Min Jian, Oscar Ka-Fai et al. · Molecular Psychiatry · 2020 · 97 citations

Medicine, Neuroscience, Pharmacology +14

Aquaporin-4 Autoantibodies From Neuromyelitis Optica Spectrum Disorder Patients Induce Complement-Independent Immunopathologies in Mice

Leung-Wah Yick, Oscar Ka-Fai, Roy Chun-Laam Ng et al. · Frontiers in Immunology · 2018 · 52 citations · Full text

Life Sciences, Neurology, Autoimmunity +16