G L DeGraaf

An orally active inhibitor of renin.

Donald T. Pals, Suvit Thaisrivongs, Judy A. Lawson et al. · Hypertension · 1986 · 62 citations

Medicine, Pharmacology, Molecular Pharmacology +12

Pretreatment with a blocking monoclonal antibody to P-selectin accelerates pharmacological thrombolysis in a primate model of arterial thrombosis.

Christopher F. Toombs, G L DeGraaf, Joseph P. Martin et al. · Journal of Pharmacology and Experimental Therapeutics · 1995 · 45 citations

Medicine, Pharmacology, Pharmacotherapy +17

Hormonal and cardiovascular effects of losartan (DuP753), an angiotensin receptor antagonist, in nonhuman primates.

G L DeGraaf, Donald T. Pals, S J Couch et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 18 citations

Medicine, Pharmacology, Physiology +17

Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin-infused rat model and in conscious sodium-depleted monkeys

Suvit Thaisrivongs, Donald T. Pals, Donald W. DuCharme et al. · Journal of Medicinal Chemistry · 1991 · 14 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Appraisal of a glycopeptide cloaking strategy for a therapeutic oligopeptide: Glycopeptide analogs of the renin inhibitor ditekiren

Allen W. Harrison, Jed F. Fisher, David M. Guido et al. · Bioorganic & Medicinal Chemistry · 1994 · 12 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13