Leen Heirbaut

Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

Koen Jansen, Leen Heirbaut, Robert Verkerk et al. · Journal of Medicinal Chemistry · 2014 · 264 citations · Full text

Structure–activity Relationship, Drug Target, Cellular Pharmacology +17

Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold

Koen Jansen, Leen Heirbaut, Jonathan D. Cheng et al. · ACS Medicinal Chemistry Letters · 2013 · 246 citations · Full text

Bioorganic Chemistry, Selective Inhibitors, Chemical Biology +17

Selective inhibitors of fibroblast activation protein (FAP) with a xanthine scaffold

Koen Jansen, Hans De Winter, Leen Heirbaut et al. · MedChemComm · 2014 · 23 citations

Peptide Engineering, Xanthine Scaffold, Selective Inhibitors +17

Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: the impact of P1-variation

Leen Heirbaut, Sebastiaan Van Goethem, Koen Jansen et al. · MedChemComm · 2015 · 12 citations

Pharmacotherapy, Chemical Biology, Experimental Pharmacology +18