Andrew Fluxe

Discovery and in vitro/in vivo studies of tetrazole derivatives as Kv1.5 blockers

Shengde Wu, Andrew Fluxe, Jim Sheffer et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 52 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Derivative (Chemistry) +9

Discovery and synthesis of tetrahydroindolone derived semicarbazones as selective Kv1.5 blockers

Shengde Wu, Andrew Fluxe, John M. Janusz et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 35 citations · Full text

Inorganic Chemistry, Medicinal Chemistry, Engineering +8

Evolution of thiazolidine-based blockers of human Kv1.5 for the treatment of atrial arrhythmias

C. M. Jackson, Benjamin E. Blass, Keith R. Coburn et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 35 citations · Full text

Human Kv1.5, Medicine, Atrial Arrhythmias +7

Synthesis and evaluation of (2-phenethyl-2H-1,2,3-triazol-4-yl)(phenyl)methanones as Kv1.5 channel blockers for the treatment of atrial fibrillation

Benjamin E. Blass, Keith R. Coburn, Wenlin Lee et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 32 citations · Full text

Medicinal Chemistry, Medicine, Kv1.5 Channel Blockers +7

Discovery and synthesis of tetrahydroindolone-derived carbamates as Kv1.5 blockers

Andrew Fluxe, Shengde Wu, James B. Sheffer et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 21 citations · Full text

Medicinal Chemistry, Natural Sciences, Organic Chemistry +3