Massively parallel digital transcriptional profiling of single cells

Grace Zheng, Jessica M. Terry, Phillip Belgrader, +30

Nature Communications

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

Garrett M. Frampton, Alex Fichtenholtz, Geoff Otto, +42

Nature Biotechnology

Dna SequencingClinical CancerEngineeringTumor HeterogeneityMedicine +10

Massively parallel digital transcriptional profiling of single cells

Grace Zheng, Jessica M. Terry, Phillip Belgrader, +29

ImmunologySingle CellsTranscriptomics TechnologyImmune SystemGene Expression Profiling +15

Haplotyping germline and cancer genomes with high-throughput linked-read sequencing

Grace Zheng, Billy T. Lau, Michael Schnall-Levin, +55

Nature Biotechnology

Long-read SequencingSequencingMedicineGeneticsNext-generation Sequencing +5

Health and population effects of rare gene knockouts in adult humans with related parents

Vagheesh M. Narasimhan, Karen A. Hunt, Dan Mason, +32

Science

Resolving the full spectrum of human genome variation using Linked-Reads

Patrick Marks, Sarah Garcia, Álvaro Martínez Barrio, +41

Genome Research

A hybrid approach for de novo human genome sequence assembly and phasing

Yulia Mostovoy, Michal Levy‐Sakin, Jessica Lam, +13

Nature Methods

HybridizationGeneticsHybrid ApproachNatural SciencesSequence Analysis +9

Conserved microRNA targeting in <i>Drosophila</i> is as widespread in coding regions as in 3′UTRs

Michael Schnall-Levin, Yong Zhao, Norbert Perrimon, +1

Proceedings of the National Academy of Sciences

BiologyBioinformaticsTranscriptional RegulationSystems BiologyDrosophila 5'Utrs +12

Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs

Michael Schnall-Levin, Olivia S. Rissland, Wendy K. Johnston, +3

Genome Research

Extensive sequencing of seven human genomes to characterize benchmark reference materials

Justin M. Zook, David Catoe, Jennifer McDaniel, +46

EngineeringBenchmark Reference MaterialsGeneticsMolecular BiologyGenomics +22