Caitlin Lynch

A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells

Leslie M. Tompkins, Haishan Li, Linhao Li et al. · Biochemical Pharmacology · 2010 · 72 citations · Full text

Signal Transduction, Biochemistry, Molecular Pathway +11

Identification of Novel Activators of Constitutive Androstane Receptor from FDA-Approved Drugs by Integrated Computational and Biological Approaches

Caitlin Lynch, Yongmei Pan, Linhao Li et al. · Pharmaceutical Research · 2012 · 47 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +10

Expanding biological space coverage enhances the prediction of drug adverse effects in human using in vitro activity profiles

Ruili Huang, Menghang Xia, Srilatha Sakamuru et al. · Scientific Reports · 2018 · 45 citations · Full text

Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor

Caitlin Lynch, Jinghua Zhao, Ruili Huang et al. · Scientific Reports · 2015 · 42 citations · Full text

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space

Sara E. Kearney, Gergely Zahoránszky-Köhalmi, Kyle R. Brimacombe et al. · ACS Central Science · 2018 · 42 citations · Full text