Fernando Morales

Somatic instability of the expanded CTG triplet repeat in myotonic dystrophy type 1 is a heritable quantitative trait and modifier of disease severity

Fernando Morales, Jillian M. Couto, Catherine F. Higham et al. · Human Molecular Genetics · 2012 · 179 citations · Full text

MSH3 modifies somatic instability and disease severity in Huntington’s and myotonic dystrophy type 1

Michael Flower, Vilija Lomeikaite, Marc Ciosi et al. · Brain · 2019 · 161 citations · Full text

A polymorphism in the MSH3 mismatch repair gene is associated with the levels of somatic instability of the expanded CTG repeat in the blood DNA of myotonic dystrophy type 1 patients

Fernando Morales, Melissa Vásquez, Carolina Santamaría et al. · DNA repair · 2016 · 80 citations · Full text

Genetic Disorder, Genetics, Clinical Genetics +8

High levels of somatic DNA diversity at the myotonic dystrophy type 1 locus are driven by ultra-frequent expansion and contraction mutations

Catherine F. Higham, Fernando Morales, Christina A. Cobbold et al. · Human Molecular Genetics · 2012 · 56 citations · Full text

Disease Progression, Repeat Length Evolution, Genetics +18

Longitudinal increases in somatic mosaicism of the expanded CTG repeat in myotonic dystrophy type 1 are associated with variation in age-at-onset

Fernando Morales, Melissa Vásquez, Eyleen Corrales et al. · Human Molecular Genetics · 2020 · 50 citations · Full text

Allelic Variant, Developmental Biology, Allele Length Distribution +15