Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures

Isabelle Morel, Gérard Lescoat, Pascale Cogrel, +5

Biochemical Pharmacology

PolyphenolicsBiochemistryMedicinePhysiologyIron-chelating Activities +7

Prolonged Maintenance of Active Cytochrome P-450 in Adult Rat Hepatocytes Co-Cultured with Another Liver Cell Type

Jean‐Marc Bégué, Christiane Guguen‐Guillouzo, Nicole Pasdeloup, +1

Hepatology

Kinetic evaluation of free malondialdehyde and enzyme leakage as indices of iron damage in rat hepatocyte cultures

Isabelle Morel, Gérard Lescoat, Josiane Cillard, +3

Biochemical Pharmacology

HepatologyBiochemistryEnzyme LeakageLiver PhysiologyPhysiology +12

Antioxidant and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: Comparison of their mechanism of protection with that of desferrioxamine

Isabelle Morel, Josiane Cillard, Gérard Lescoat, +6

Free Radical Biology and Medicine

BiochemistryMedicineLipid PeroxidationHepatotoxicityIron Chelators +7

The new orally active iron chelator ICL670A exhibits a higher antiproliferative effect in human hepatocyte cultures than O-trensox

Karine Chantrel-Groussard, François Gaboriau, Nicole Pasdeloup, +5

European Journal of Pharmacology

HepatologyBiochemistryMedicineLiver PhysiologyHepatotoxicity +7

Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism

Gérard Lescoat, Karine Chantrel-Groussard, Nicole Pasdeloup, +3

Cell Proliferation

Simultaneous measurements of conjugated dienes and free malondialdehyde, used as a micromethod for the evaluation of lipid peroxidation in rat hepatocyte cultures

Odile Sergent, Isabelle Morel, Pascale Cogrel, +6

Chemistry and Physics of Lipids

Free MalondialdehydeBiochemistryMedicineLiver PhysiologyLipid Peroxidation +8

Increase in cellular pool of low-molecular-weight iron during ethanol metabolism in rat hepatocyte cultures

Odile Sergent, Isabelle Morel, Pascale Cogrel, +6

Biological Trace Element Research

Iron MetabolismEthanol MetabolismRedox BiologyOxidative StressHepatotoxicity +16

Inhibition of iron toxicity in rat hepatocyte culture by natural phenolic compounds

H. Chimi, Isabelle Morel, Gérard Lescoat, +3

Toxicology in Vitro

PolyphenolicsRat Hepatocyte CultureBiochemistryMedicineLiver Physiology +12

Inhibition of iron toxicity in rat and human hepatocyte cultures by the hydroxypyridin-4-ones CP20 and CP94

Norchen Chenoufi, N. Hubert, Olivier Loréal, +5

Journal of Hepatology

BiochemistryHeme HomeostasisMedicineLiver PhysiologyHydroxypyridin-4-ones Cp20 +13