Pooja Gopal

Phase variation in <i>Mycobacterium tuberculosis glpK</i> produces transiently heritable drug tolerance

Hassan Safi, Pooja Gopal, Subramanya Lingaraju et al. · Proceedings of the National Academy of Sciences · 2019 · 148 citations · Full text

Medicine, Molecular Biology, Molecular Genetics +13

Pyrazinamide triggers degradation of its target aspartate decarboxylase

Pooja Gopal, Jickky Palmae Sarathy, Michelle Yee et al. · Nature Communications · 2020 · 121 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Pyrazinamide Resistance Is Caused by Two Distinct Mechanisms: Prevention of Coenzyme A Depletion and Loss of Virulence Factor Synthesis

Pooja Gopal, Michelle Yee, Jickky Palmae Sarathy et al. · ACS Infectious Diseases · 2016 · 95 citations · Full text

Life Sciences, Genetics, Microbiology +16

Exquisitely Specific anti-KRAS Biodegraders Inform on the Cellular Prevalence of Nucleotide-Loaded States

Shuhui Lim, Regina Khoo, Yu‐Chi Juang et al. · ACS Central Science · 2020 · 86 citations · Full text

Medicine, Molecular Biology, Oncology +15

Host-Mediated Bioactivation of Pyrazinamide: Implications for Efficacy, Resistance, and Therapeutic Alternatives

Laura E. Via, Rada Savic, Matthew Zimmerman et al. · ACS Infectious Diseases · 2015 · 77 citations

Medicine, Pharmacokinetics, Pharmacology +17