Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease

Sangjune Kim, Seung‐Hwan Kwon, Tae‐In Kam, +16

Neuron

Transneuronal PropagationNeurodegenerative DiseasesSynaptic SignalingSynaptic TransmissionDegenerative Pathology +8

The Shaping of Modern Human Immune Systems by Multiregional Admixture with Archaic Humans

Laurent Abi‐Rached, Matthew J. Jobin, Subhash Kulkarni, +20

Science

HistocompatibilityArchaic AllelesAdaptive Immune SystemGeneticsArtificial Immune System +18

Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis

Subhash Kulkarni, Maria-Adelaide Micci, Jenna Leser, +19

Proceedings of the National Academy of Sciences

Identification of a cKit+ Colonic Crypt Base Secretory Cell That Supports Lgr5+ Stem Cells in Mice

Michael E. Rothenberg, Ysbrand Nusse, Tomer Kalisky, +11

Gastroenterology

Induced Pluripotent Stem CellMedicineAdult Stem CellImmunologyStem Cell Research +4

Age-dependent shift in macrophage polarisation causes inflammation-mediated degeneration of enteric nervous system

Laren Becker, Linh P. Nguyen, Jaspreet Kaur Gill, +3

Gut

Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells

Charles K. F. Chan, Paul Lindau, Wen Jiang, +23

Proceedings of the National Academy of Sciences

Progenitor CellsAdult Stem CellImmunologyCell SpecializationOrthopaedic Surgery +14

Intestinal Bacteria Maintain Adult Enteric Nervous System and Nitrergic Neurons via Toll-like Receptor 2-induced Neurogenesis in Mice

Shadi Yarandi, Subhash Kulkarni, Monalee Saha, +3

Gastroenterology

Toll-like ReceptorsNitrergic NeuronsDysbiosisMucosal ImmunologyMedicine +10

Simultaneous optical and electrical in vivo analysis of the enteric nervous system

Nikolai Rakhilin, Bradley B. Barth, Jiahn Choi, +13

Nature Communications

Biomedical EngineeringOptogeneticsOptic NerveNeurochipSocial Sciences +18

Lymphatic vessel remodeling and invasion in pancreatic cancer progression

Chia‐Ning Shen, King-Siang Goh, Chi‐Ruei Huang, +12

EBioMedicine

Ex Vivo Neurogenesis within Enteric Ganglia Occurs in a PTEN Dependent Manner

Laren Becker, Johann Peterson, Subhash Kulkarni, +1

PLoS ONE