ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo

Carlos Barcia, Carmen María Brugarolas Ros, Valentina Annese, +8

Scientific Reports

Metalloproteinase-9 contributes to inflammatory glia activation and nigro-striatal pathway degeneration in both mouse and monkey models of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism

Valentina Annese, María Trinidad Herrero, M. Di Pentima, +6

Brain Structure and Function

Monkey ModelsMedicineNeuropharmacologyMetalloproteinase-9 ContributesNeuroprotection +9

Increased plasma levels of TNF-α but not of IL1-β in MPTP-treated monkeys one year after the MPTP administration

Carlos Barcia, Vicente de Pablos, Víctor Bautista‐Hernández, +7

Parkinsonism & Related Disorders

InflammationMptp-treated Monkeys OneCytokineMptp AdministrationPlasma Levels +8

Persistent phagocytic characteristics of microglia in the substantia nigra of long-term Parkinsonian macaques

Carlos Barcia, Carmen María Brugarolas Ros, Francisco Ros‐Bernal, +8

Journal of Neuroimmunology

Neurobiology Of DiseaseLong-term Parkinsonian MacaquesSubstantia NigraMedicineImmunology +10

Nigral degeneration correlates with persistent activation of cerebellar Purkinje cells in MPTP-treated monkeys.

P Heman, Carlos Barcia, Carmen María Brugarolas Ros, +6

PubMed

Cellular NeurobiologyLong Term ActivationSocial SciencesPersistent ActivationNeurobiology Of Disease +15

Evidence of oligodendrogliosis in 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)‐induced Parkinsonism

Valentina Annese, Carlos Barcia, Francisco Ros‐Bernal, +6

Neuropathology and Applied Neurobiology

CD20, CD3, and CD40 Ligand Microclusters Segregate Three-Dimensionally In Vivo at B-Cell-T-Cell Immunological Synapses after Viral Immunity in Primate Brain

Carlos Barcia, Aurora Gómez, Vicente de Pablos, +8

Journal of Virology

ImmunologyImmunodominanceImmunologic MechanismAntigen ProcessingPersistent Infiltration +14

Measurement of motor disability in MPTP-treated macaques using a telemetry system for estimating circadian motor activity

Carlos Barcia, Vicente de Pablos, Víctor Bautista‐Hernández, +4

Journal of Neuroscience Methods

SleepAssistive TechnologyMotor DisabilityMedicineTelemetry System +13

MPTP administration increases plasma levels of acute phase proteins in non-human primates (Macaca fascicularis)

Vicente de Pablos, Carlos Barcia, Abraham Bernárdez-Gómez, +5

Neuroscience Letters

Animal PhysiologyInflammationNeuropeptidesAcute Phase ProteinsMedicine +9

Cardiac Noradrenaline Turnover and Heat Shock Protein 27 Phosphorylation in Dyskinetic Monkeys

Pilar Almela, Lorena Cuenca‐Bermejo, José Enrique Yuste, +6

Movement Disorders