Karine Jacob

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu et al. · Nature · 2012 · 2.7K citations

Medicine, Genetics, Oncology +16

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

Dominik Sturm, Hendrik Witt, Volker Hovestadt et al. · Cancer Cell · 2012 · 1.9K citations · Full text

Medicine, Genetics, Molecular Genetics +16

<i>BRAF-KIAA1549</i> Fusion Predicts Better Clinical Outcome in Pediatric Low-Grade Astrocytoma

Cynthia Hawkins, Erin J. Walker, Nequesha S. Mohamed et al. · Clinical Cancer Research · 2011 · 241 citations

Medicine, Genetics, Oncology +17

Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

Huriye Cin, Claus Meyer, Ricarda Herr et al. · Acta Neuropathologica · 2011 · 238 citations

Medicine, Molecular Genetics, Oncology +16

Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours

Karine Jacob, Steffen Albrecht, Caroline Sollier et al. · British Journal of Cancer · 2009 · 183 citations · Full text

Life Sciences, Genetics, Oncology +14