Concepedia

Charles A. Ishak

CA

15

Publications

926

Citations

13

H-Index

2014

Active since

Affiliations

University of Toronto(Current)

University Health Network

Princess Margaret Cancer Centre

Western University

Children’s Health Research Institute

Charles A. Ishak is an author at University of Toronto specializing in medicine, transcriptional regulation, and gene expression.

Top concepts

MedicineTranscriptional RegulationGeneticsChromatinEpigeneticsCell BiologyGene ExpressionMolecular BiologyNatural SciencesEpigenomics

Publications per year

2014–2025

15

Publications

15

Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency

Parinaz Mehdipour, Sajid A. Marhon, Ilias Ettayebi et al. · Nature · 2020 · 269 citations

Chromatin, Transcriptional Regulation, Chromatin Remodeling +9

An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences

Charles A. Ishak, Aren E. Marshall, Daniel T. Passos et al. · Molecular Cell · 2016 · 166 citations · Full text

Chromatin, Genome Instability, Transcriptional Regulation +9

DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells

Helen Loo Yau, Emma Bell, Ilias Ettayebi et al. · Molecular Cell · 2021 · 85 citations · Full text

Cytolytic Activity, T-regulatory Cell, Immunology +9

Haploinsufficiency of an RB–E2F1–Condensin II Complex Leads to Aberrant Replication and Aneuploidy

Courtney H. Coschi, Charles A. Ishak, David Gallo et al. · Cancer Discovery · 2014 · 82 citations · Full text

An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors

Kirsty Taylor, Helen Loo Yau, Ankur Chakravarthy et al. · Journal for ImmunoTherapy of Cancer · 2020 · 66 citations · Full text

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