Charles A. Ishak

Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency

Parinaz Mehdipour, Sajid A. Marhon, Ilias Ettayebi et al. · Nature · 2020 · 286 citations

Life Sciences, Genetics, Molecular Biology +11

An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences

Charles A. Ishak, Aren E. Marshall, Daniel T. Passos et al. · Molecular Cell · 2016 · 167 citations · Full text

Life Sciences, Genetics, Molecular Biology +7

DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells

Helen Loo Yau, Emma Bell, Ilias Ettayebi et al. · Molecular Cell · 2021 · 87 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Haploinsufficiency of an RB–E2F1–Condensin II Complex Leads to Aberrant Replication and Aneuploidy

Courtney H. Coschi, Charles A. Ishak, David Gallo et al. · Cancer Discovery · 2014 · 84 citations · Full text

Life Sciences, Genetics, Oncology +17

An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors

Kirsty Taylor, Helen Loo Yau, Ankur Chakravarthy et al. · Journal for ImmunoTherapy of Cancer · 2020 · 70 citations · Full text

Medicine, Oncology, Pharmacology +17