Pan-cancer image-based detection of clinically actionable genetic alterations

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Nature Cancer

EngineeringMedicineDigital PathologyPathologyCancer Genomics +7

The impact of site-specific digital histology signatures on deep learning model accuracy and bias

Frederick M. Howard, James M. Dolezal, Sara Kochanny, +10

Nature Communications

OPTIMA: a phase II dose and volume de-escalation trial for human papillomavirus-positive oropharyngeal cancer

Tanguy Y. Seiwert, Corey C. Foster, Elizabeth A. Blair, +13

Annals of Oncology

Circulating Tumor DNA Sequencing Analysis of Gastroesophageal Adenocarcinoma

Steven B. Maron, Leah M. Chase, Samantha Lomnicki, +11

Clinical Cancer Research

Machine Learning–Guided Adjuvant Treatment of Head and Neck Cancer

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JAMA Network Open

Uncertainty-informed deep learning models enable high-confidence predictions for digital histopathology

James M. Dolezal, Andrew Srisuwananukorn, Dmitry Karpeyev, +13

Nature Communications

Immune‐related adverse events are associated with improved response, progression‐free survival, and overall survival for patients with head and neck cancer receiving immune checkpoint inhibitors

Corey C. Foster, Marcus Couey, Sara Kochanny, +6

Cancer

Deep learning generates synthetic cancer histology for explainability and education

James M. Dolezal, Rachelle Wolk, Hanna M. Hieromnimon, +20

npj Precision Oncology

Deep learning prediction of BRAF-RAS gene expression signature identifies noninvasive follicular thyroid neoplasms with papillary-like nuclear features

James M. Dolezal, Anna Trzcinska, Chih‐Yi Liao, +7

Modern Pathology

Integration of clinical features and deep learning on pathology for the prediction of breast cancer recurrence assays and risk of recurrence

Frederick M. Howard, James M. Dolezal, Sara Kochanny, +10

npj Breast Cancer