Amber D. Bowler

Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants

Christopher A. Eide, Matthew S. Zabriskie, Samantha L. Savage et al. · Cancer Cell · 2019 · 245 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +11

Neutrophils suppress tumor‐infiltrating T cells in colon cancer via matrix metalloproteinase‐mediated activation of TGFβ

Markus Germann, Nadine Zangger, Marc‐Olivier Sauvain et al. · EMBO Molecular Medicine · 2019 · 167 citations · Full text

Medicine, Immunology, Oncology +17

Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo

L. Francisco Lorenzo‐Martín, Tania Hübscher, Amber D. Bowler et al. · Nature · 2024 · 96 citations · Full text

Medicine, Cancer Biology, Oncology +17

shRNA library screening identifies nucleocytoplasmic transport as a mediator of BCR-ABL1 kinase-independent resistance

Jamshid S. Khorashad, Anna M. Eiring, Clinton C. Mason et al. · Blood · 2015 · 44 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +12

β-Catenin is required for intrinsic but not extrinsic BCR-ABL1 kinase-independent resistance to tyrosine kinase inhibitors in chronic myeloid leukemia

Anna M. Eiring, Jamshid S. Khorashad, David Anderson et al. · Leukemia · 2015 · 43 citations

Medicine, Cancer Biology, Oncology +16