Enhanced optineurin E50K–TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma

Yuriko Minegishi, Daisuke Iejima, Hiroaki Kobayashi, +7

Human Molecular Genetics

Neurodegenerative DiseasesOcular DiseaseMolecular PhysiologySignal TransductionOphthalmology +12

Overexpression of<i>HtrA1</i>and Exposure to Mainstream Cigarette Smoke Leads to Choroidal Neovascularization and Subretinal Deposits in Aged Mice

Mao Nakayama, Daisuke Iejima, Masakazu Akahori, +3

Investigative Ophthalmology & Visual Science

CCT2 Mutations Evoke Leber Congenital Amaurosis due to Chaperone Complex Instability

Yuriko Minegishi, Xunlun Sheng, Kazutoshi Yoshitake, +11

Scientific Reports

A Compact, Automated Cell Culture System for Clinical Scale Cell Expansion from Primary Tissues

Ryuji Kato, Daisuke Iejima, Hideki Agata, +5

Tissue Engineering Part C Methods

Tissue EngineeringCell TherapyPrimary TissuesEngineeringCell Culture Systems +15

Differential Inducibility of Human and Porcine Dental Pulp-Derived Cells into Odontoblasts

Akiko Tonomura, Yoshinori Sumita, Daisuke Iejima, +3

Connective Tissue Research

Tissue EngineeringEngineeringAdult Stem CellBiomedical EngineeringOsteoporosis +19

Clinical and Genetic Characteristics of 18 Patients from 13 Japanese Families with CRX-associated retinal disorder: Identification of Genotype-phenotype Association

Yu Fujinami‐Yokokawa, Kaoru Fujinami, Kazuki Kuniyoshi, +83

Scientific Reports

HTRA1 (High Temperature Requirement A Serine Peptidase 1) Gene Is Transcriptionally Regulated by Insertion/Deletion Nucleotides Located at the 3′ End of the ARMS2 (Age-related Maculopathy Susceptibility 2) Gene in Patients with Age-related Macular Degeneration

Daisuke Iejima, Takeshi Itabashi, Yuich Kawamura, +5

Journal of Biological Chemistry

METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma

Yang Pan, Akiko Suga, Itaru Kimura, +15

Journal of Clinical Investigation

Histone ModificationsEpigenetic ChangeGeneticsRetinal Ganglion CellGene Characterization +23

Odontoblast marker gene expression is enhanced by a CC-chemokine family protein MIP-3α in human mesenchymal stem cells

Daisuke Iejima, Yoshinori Sumita, Hideaki Kagami, +2

Archives of Oral Biology

Regenerative MedicineDevelopmental BiologyMedicineAdult Stem CellOral Biology +7

HTRA1 Overexpression Induces the Exudative Form of Age-related Macular Degeneration.

Daisuke Iejima, Mao Nakayama, Takeshi Iwata

PubMed

Ocular DiseasePromoter RegionAgingOphthalmologyDegenerative Diseases +11