The association between sterilizing activity and drug distribution into tuberculosis lesions

Brendan Prideaux, Laura E. Via, Matthew Zimmerman, +15

Nature Medicine

Pulmonary TuberculosisTuberculosis LesionsTuberculosis PreventionTuberculosisTuberculosis Diagnostics +3

Tuberculosis drugs’ distribution and emergence of resistance in patient’s lung lesions: A mechanistic model and tool for regimen and dose optimization

Natasha Strydom, Sneha Gupta, William S. Fox, +9

PLoS Medicine

Extensive Drug Resistance Acquired During Treatment of Multidrug-Resistant Tuberculosis

J. Peter Cegielski, Tracy Dalton, Martín Yagui, +75

Clinical Infectious Diseases

Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy

Michelle M. Bellerose, Seung-Hun Baek, Chuan‐Chin Huang, +11

mBio

IL-13 may mediate allergen-induced hyperresponsiveness independently of IL-5 or eotaxin by effects on airway smooth muscle

Seok‐Yong Eum, Karim Maghni, Barbara Tolloczko, +2

American Journal of Physiology-Lung Cellular and Molecular Physiology

InflammationCytokineAllergyInflammatory Lung DiseaseLung Inflammation +11

Rapid detection of Mycobacterium tuberculosis biomarkers in a sandwich immunoassay format using a waveguide-based optical biosensor

Harshini Mukundan, Sandeep Kumar, Dominique N. Price, +14

Tuberculosis

Photonic SensorPulmonary TuberculosisMycobacterium Tuberculosis BiomarkersWaveguide-based Optical BiosensorEngineering +11

Nitric Oxide and Protein Nitration are Eosinophil Dependent in Allergen-Challenged Mice

Hiroaki Iijima, Alexandre Duguet, Seok‐Yong Eum, +2

American Journal of Respiratory and Critical Care Medicine

Acute Lung InjuryAsthmaInflammatory Lung DiseaseLung InflammationNitric Oxide +23

Efficacy and Safety of Metronidazole for Pulmonary Multidrug-Resistant Tuberculosis

Matthew Carroll, Doosoo Jeon, James M. Mountz, +21

Antimicrobial Agents and Chemotherapy

Peripheral NeuropathyPulmonary TuberculosisAntibioticsTuberculosis PreventionPharmacology +10

Host-Mediated Bioactivation of Pyrazinamide: Implications for Efficacy, Resistance, and Therapeutic Alternatives

Laura E. Via, Rada Savic, Matthew Zimmerman, +16

ACS Infectious Diseases

Antiparasitic AgentImmunologyPharmacotherapyPharmaceutical ChemistryLung Tissue +16

Polymorphisms Associated with Resistance and Cross-Resistance to Aminoglycosides and Capreomycin in <i>Mycobacterium tuberculosis</i> Isolates from South Korean Patients with Drug-Resistant Tuberculosis

Laura E. Via, Sang-Nae Cho, Soo-Hee Hwang, +18

Journal of Clinical Microbiology

Polymorphisms AssociatedTuberculosis PreventionAntibiotic ResistanceDrug ResistanceMycobacterium Tuberculosis +18