Characterization of the estrogenic activities of zearalenone and zeranol in vivo and in vitro

Hitomi Takemura, Joong‐Youn Shim, Kazutoshi Sayama, +3

The Journal of Steroid Biochemistry and Molecular Biology

Hormonal ContraceptiveEstrogenic ActivitiesMedicineHormonal ReceptorGynecology +5

Selective inhibition of methoxyflavonoids on human CYP1B1 activity

Hitomi Takemura, Toshimasa Itoh, Keiko Yamamoto, +2

Bioorganic & Medicinal Chemistry

Translational PharmacologyBiochemistryMedicinePharmacotherapyPharmacology +3

In vitro and in vivo estrogenic activity of chlorinated derivatives of bisphenol A

Hitomi Takemura, Jie Ma, Kazutoshi Sayama, +3

Toxicology

Endocrine DisruptorsMedicinal ChemistryDerivative (Chemistry)BiochemistryVivo Estrogenic Activity +10

Inhibitory effects of chrysoeriol on DNA adduct formation with benzo[a]pyrene in MCF-7 breast cancer cells

Hitomi Takemura, Haruna Nagayoshi, Tomonari Matsuda, +5

Toxicology

Dna Adduct FormationInhibitory EffectsBreast OncologyOncogenic AgentMedicine +7

Synergistic activation of ERK1/2 between A-fiber neurons and glial cells in the DRG contributes to pain hypersensitivity after tissue injury

Shunsuke Yamakita, Yasuhiko Horii, Hitomi Takemura, +6

Molecular Pain

Pain DisordersPeripheral Nerve InjuryPain MedicineSynaptic TransmissionNeuromodulation Therapies +27

A 3D Model of CYP1B1 Explains the Dominant 4-Hydroxylation of Estradiol

Toshimasa Itoh, Hitomi Takemura, Kayoko Shimoi, +1

Journal of Chemical Information and Modeling

Crystal StructureProtein AssemblyMolecular BiologyHomology ModelingChemical Biology +15

A methoxyflavonoid, chrysoeriol, selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells

Hitomi Takemura, Harue Uchiyama, Takeshi Ohura, +4

The Journal of Steroid Biochemistry and Molecular Biology

Breast OncologyMedicineBreast CancerAnti-cancer AgentCarcinogenic Estrogen Metabolite +3

Endoplasmic Reticulum Stress in the Dorsal Root Ganglion Contributes to the Development of Pain Hypersensitivity after Nerve Injury

Yosuke Yamaguchi, Kentaro Oh‐hashi, Yutaka Matsuoka, +5

Neuroscience

Pain SyndromeSpinal Cord InjuryHealth SciencesAcute PainNeuroanatomy +13

Post‐surgical chronic pain and quality of life in children operated for congenital heart disease

Megumi Matsuda, Hitomi Takemura, Ayahiro Yamashita, +3

Acta Anaesthesiologica Scandinavica

Quercetin-3-O-glucronide inhibits noradrenaline binding to α2-adrenergic receptor, thus suppressing DNA damage induced by treatment with 4-hydroxyestradiol and noradrenaline in MCF-10A cells

Shunsuke Yamazaki, Hiroyuki Sakakibara, Hitomi Takemura, +2

The Journal of Steroid Biochemistry and Molecular Biology

Molecular PharmacologyDna DamageEndocrine MechanismMedicinePhysiology +5