Juan Francisco Castro

Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann‐Pick type C disease

Alejandra Álvarez, Andrés D. Klein, Juan Francisco Castro et al. · The FASEB Journal · 2008 · 107 citations · Full text

Apoptosis, Pathology, Cell Death +19

MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content

Elisa Balboa, Juan Francisco Castro, María-José Pinochet et al. · Redox Biology · 2017 · 76 citations · Full text

Relevance of Niemann-Pick type C1 protein expression in controlling plasma cholesterol and biliary lipid secretion in mice

Ludwig Amigo, Hegaly Mendoza, Juan Francisco Castro et al. · Hepatology · 2002 · 65 citations · Full text

Npc1 deficiency in the C57BL/6J genetic background enhances Niemann–Pick disease type C spleen pathology

Julio Parra, Andrés D. Klein, Juan Francisco Castro et al. · Biochemical and Biophysical Research Communications · 2011 · 50 citations · Full text

C57bl/6j Genetic Background, Disease Mechanism, Genetic Disorder +9

c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder

Pablo S. Contreras, Pablo Tapía, Lila González-Hódar et al. · iScience · 2020 · 43 citations · Full text