Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

Matthew M. Gubin, Xiuli Zhang, Heiko Schuster, +24

Nature

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

Hirokazu Matsushita, Matthew D. Vesely, Daniel C. Koboldt, +16

Nature

Cancer ImmunosurveillanceCancer ImmunoeditingT-regulatory CellImmunologyImmunoediting +5

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

Mark S. Diamond, Michelle Kinder, Hirokazu Matsushita, +9

The Journal of Experimental Medicine

Disruption of the Jak1 Gene Demonstrates Obligatory and Nonredundant Roles of the Jaks in Cytokine-Induced Biologic Responses

Scott J. Rodig, Marco Antonio Meraz‐Ríos, J. Michael White, +9

Cell

InflammationCytokineSignal TransductionAutoimmune DiseaseReceptor Tyrosine Kinase +11

MHC-II neoantigens shape tumour immunity and response to immunotherapy

Elise Alspach, Danielle M. Lussier, Alexander P. Miceli, +20

Nature

Tumor ImmunologyCancer ImmunosurveillanceMhc-ii NeoantigensImmunologyTumor Immunity +4

A critical function for type I interferons in cancer immunoediting

Gavin P. Dunn, Allen T. Bruce, Kathleen C. F. Sheehan, +8

Nature Immunology

Cancer ImmunosurveillanceImmunologyTumor ImmunityPathologyImmunologic Mechanism +7

Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice

Yin Li, Lin Wu, Holger Wesche, +4

Science

Immune RegulationImmunologyCell DeathImmunologic MechanismNik-deficient Mice +15

High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy

Matthew M. Gubin, Ekaterina Esaulova, Jeffrey P. Ward, +16

Cell

Tumor BiologyLymphoid NeoplasiaMedicineMalignant Blood DisorderImmunology +7

Cancer immunoediting by the innate immune system in the absence of adaptive immunity

Timothy E. O’Sullivan, Robert Saddawi‐Konefka, William Vermi, +10

The Journal of Experimental Medicine

Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape

Takuro Noguchi, Jeffrey P. Ward, Matthew M. Gubin, +8

Cancer Immunology Research