The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma

Parvez Vora, Chitra Venugopal, Sabra K. Salim, +25

Cell stem cell

Neuro-oncologyRational DevelopmentImmunologyImmune Checkpoint InhibitorImmunotherapeutics +4

Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease

Elyse Rosa, Sujeivan Mahendram, Yazi D. Ke, +3

Neurobiology of Aging

Bdnf ExpressionAlzheimer's DiseaseCellular ModelsCell DeathDegenerative Pathology +8

STAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation

Mohini Singh, Neha Garg, Chitra Venugopal, +22

Oncotarget

CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence

Neha Garg, David Bakhshinyan, Chitra Venugopal, +17

Oncogene

Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells

Chitra Venugopal, Robin Hallett, Parvez Vora, +17

Clinical Cancer Research

BMI1 is a therapeutic target in recurrent medulloblastoma

David Bakhshinyan, Chitra Venugopal, Ashley Adile, +35

Oncogene

Hematological MalignancyNeuro-oncologyPathologyMedicineGlioma +1

A Single TCF Transcription Factor, Regardless of Its Activation Capacity, Is Sufficient for Effective Trilineage Differentiation of ESCs

Steven Moreira, Enio Polena, Victor Gordon, +7

Cell Reports

RNAi screen identifies essential regulators of human brain metastasis-initiating cells

Mohini Singh, Chitra Venugopal, Tomáš Tokár, +19

Acta Neuropathologica

Neuro-oncologyDevelopmental BiologyCell RegulationMedicineCancer Biology +2

The identification of human pituitary adenoma-initiating cells

Branavan Manoranjan, Sujeivan Mahendram, Saleh A. Almenawer, +10

Acta Neuropathologica Communications

Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells

Parvez Vora, Mathieu Seyfrid, Chitra Venugopal, +16

Journal of Neuro-Oncology

Neuro-oncologyLineage PlasticityDifferential Gene NetworksDevelopmental BiologyGlioma +7