Souren Mkrtchian

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Catherine C. Bell, Delilah Hendriks, Sabrina Moro et al. · Scientific Reports · 2016 · 708 citations · Full text

Medicine, Pharmacology, Toxicology +17

Integrating rare genetic variants into pharmacogenetic drug response predictions

Magnus Ingelman‐Sundberg, Souren Mkrtchian, Yitian Zhou et al. · Human Genomics · 2018 · 215 citations · Full text

Medicine, Molecular Genetics, Pharmacology +14

ERp29 Triggers a Conformational Change in Polyomavirus to Stimulate Membrane Binding

Brian Magnuson, Emily K. Rainey, Thomas L. Benjamin et al. · Molecular Cell · 2005 · 160 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

An optimized prediction framework to assess the functional impact of pharmacogenetic variants

Yitian Zhou, Souren Mkrtchian, Masaki Kumondai et al. · The Pharmacogenomics Journal · 2018 · 151 citations · Full text

Life Sciences, Bioinformatics, Genetics +16

Hormone- and substrate-regulated intracellular degradation of cytochrome P450 (2E1) involving MgATP-activated rapid proteolysis in the endoplasmic reticulum membranes.

Erik Eliasson, Souren Mkrtchian, Magnus Ingelman‐Sundberg · Journal of Biological Chemistry · 1992 · 119 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17