Concepedia
Statistics
Publications
11
Citations
510
H-Index
Active since
2020
Affiliations
University of Victoria(Current)
University of British Columbia
VIB-VUB Center for Structural Biology
Max Perutz Labs
Medical University of Vienna
Kaelin D. Fleming is an author at University of Victoria specializing in life sciences, biochemistry, and molecular biology.
Publications per year
2020–2023
Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation
Aleksandra Levina, Kaelin D. Fleming, John E. Burke et al. · Nature Communications · 2022 · 105 citations · Full text
Life Sciences, Cell Biology, Molecular Biology +12
Structure of autoinhibited Akt1 reveals mechanism of PIP <sub>3</sub> -mediated activation
Linda Truebestein, Harald Hornegger, Dorothea Anrather et al. · Proceedings of the National Academy of Sciences · 2021 · 90 citations · Full text
Life Sciences, Cell Biology, Molecular Biology +15
Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation
Manoj Kumar Rathinaswamy, Udit Dalwadi, Kaelin D. Fleming et al. · Science Advances · 2021 · 64 citations · Full text
Life Sciences, Biochemistry, Molecular Biology +16
Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors
Manoj K Rathinaswamy, Zied Gaieb, Kaelin D. Fleming et al. · eLife · 2021 · 56 citations · Full text
Life Sciences, Molecular Biology, Pharmacology +15
Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation
Yong‐Mi Choi, Dalila Ajjaji, Kaelin D. Fleming et al. · Nature Communications · 2023 · 54 citations · Full text
Life Sciences, Biochemistry, Cell Biology +17
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