Concepedia

Manuel Chan

MC

6

Publications

507

Citations

6

H-Index

1998

Active since

Affiliations

University of Toronto(Current)

Princess Margaret Cancer Centre

Ontario Institute for Cancer Research

Structural Genomics Consortium

McGill University Health Centre

Manuel Chan is an author at University of Toronto specializing in molecular biology, molecular genetics, and medicine.

Top concepts

Publications per year

1998–2024

6

Publications

6

Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)

Philippe Goyette, Aditya Pai, Renate Milos et al. · Mammalian Genome · 1998 · 358 citations

, , +5

Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms

Pamela V. Tran, Daniel Leclerc, Manuel Chan et al. · Mammalian Genome · 2002 · 58 citations

, , +11

Synergy between the NAMPT Inhibitor GMX1777(8) and Pemetrexed in Non–Small Cell Lung Cancer Cells Is Mediated by PARP Activation and Enhanced NAD Consumption

Manuel Chan, Michel Gravel, Alexandre Bramoullé et al. · Cancer Research · 2014 · 43 citations · Full text

Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity

Mark Mabanglo, Brian C. Wilson, Mahmoud Noureldin et al. · Nature Communications · 2024 · 26 citations · Full text

Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor

Ahmed Mamai, Anh Chau, Brian J. Wilson et al. · ACS Medicinal Chemistry Letters · 2023 · 12 citations · Full text

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