Kristen Ryan

Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity

Kristen Ryan, Oksana Sirenko, Fred Parham et al. · NeuroToxicology · 2016 · 135 citations

Induced Pluripotent Stem Cell, Developmental Biology, Medicine +8

In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model

Oksana Sirenko, Fabian A. Grimm, Kristen Ryan et al. · Toxicology and Applied Pharmacology · 2017 · 111 citations · Full text

Regenerative Medicine, Environmental Chemicals, Induced Pluripotent Stem Cell +15

Post-Translational Oxidative Modification and Inactivation of Mitochondrial Complex I in Epileptogenesis

Kristen Ryan, Donald S. Backos, Philip Reigan et al. · Journal of Neuroscience · 2012 · 89 citations · Full text

Molecular Biology, Temporal Lobe Epilepsy, Redox Biology +21

Functional and Mechanistic Neurotoxicity Profiling Using Human iPSC-Derived Neural 3D Cultures

Oksana Sirenko, Fred Parham, Steven Dea et al. · Toxicological Sciences · 2018 · 80 citations · Full text

Calcium Oscillation Rate, Cerebral Organoid, Biomedical Engineering +17

Rho family GTPase inhibition reveals opposing effects of mitogen‐activated protein kinase kinase/extracellular signal‐regulated kinase and Janus kinase/signal transducer and activator of transcription signaling cascades on neuronal survival

F. Alexandra Loucks, Shoshona S. Le, Angela Zimmermann et al. · Journal of Neurochemistry · 2006 · 56 citations