Structure and mechanism of the mammalian fructose transporter GLUT5

Norimichi Nomura, Grégory Verdon, Hae Joo Kang, +19

Nature

Molecular PhysiologyBiochemistryNatural SciencesProtein TransportCellular Biochemistry +2

Aldolase Is Essential for Energy Production and Bridging Adhesin-Actin Cytoskeletal Interactions during Parasite Invasion of Host Cells

G. Lucas Starnes, M. Coincon, J. Sygusch, +1

Cell Host & Microbe

Aldo-keto ReductaseParasite InvasionBiochemistryBioenergeticsCytoskeleton +7

Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters

M. Coincon, Povilas Uzdavinys, Emmanuel Nji, +6

Nature Structural & Molecular Biology

Ion TranslocationSodium/proton AntiportersIon ExchangeBiochemistryNatural Sciences +7

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

Michael Landreh, Erik G. Marklund, Povilas Uzdavinys, +8

Nature Communications

Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli

Marı́a de la Paz Santangelo, Petra Gest, Marcelo E. Guerin, +13

Journal of Biological Chemistry

Identification of the Binding Site of Brucella VirB8 Interaction Inhibitors

Mark A. Smith, M. Coincon, Athanasios Paschos, +4

Chemistry & Biology

Medicinal ChemistryNatural SciencesMedicineMechanism Of ActionMolecular Biology +5

Dissecting the proton transport pathway in electrogenic Na ⁺ /H ⁺ antiporters

Povilas Uzdavinys, M. Coincon, Emmanuel Nji, +4

Proceedings of the National Academy of Sciences

Structural basis for the delivery of activated sialic acid into Golgi for sialyation

Emmanuel Nji, Ashutosh Gulati, Abdul Aziz Qureshi, +2

Nature Structural & Molecular Biology

Molecular SieveChemical EngineeringEngineeringBiocatalysisBiochemical Engineering +2

Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases

Benoît Jacques, M. Coincon, J. Sygusch

Journal of Biological Chemistry

Selective Irreversible Inhibition of Fructose 1,6-Bisphosphate Aldolase from <i>Trypanosoma b</i><i>rucei</i>

Chantal Dax, Francis Duffieux, Nicolas Chabot, +4

Journal of Medicinal Chemistry

Medicinal ChemistryBioorganic ChemistryAldehyde DehydrogenaseBiochemistryFructose 1,6-Bisphosphate Aldolase +12