Shoichi Nishimoto

Activation of Nrf2 attenuates carbonyl stress induced by methylglyoxal in human neuroblastoma cells: Increase in GSH levels is a critical event for the detoxification mechanism

Shoichi Nishimoto, Shin Koike, Naho Inoue et al. · Biochemical and Biophysical Research Communications · 2017 · 71 citations

Reductive Stress, Biochemistry, Medicine +12

Cysteine persulfides and polysulfides produced by exchange reactions with H2S protect SH-SY5Y cells from methylglyoxal-induced toxicity through Nrf2 activation

Shin Koike, Shoichi Nishimoto, Yuki Ogasawara · Redox Biology · 2017 · 50 citations · Full text

Polysulfides protect SH-SY5Y cells from methylglyoxal-induced toxicity by suppressing protein carbonylation: A possible physiological scavenger for carbonyl stress in the brain

Shin Koike, Tasuku Kayama, Shigeyoshi Yamamoto et al. · NeuroToxicology · 2016 · 28 citations

Sh-sy5y Cells, Biochemistry, Methylglyoxal-induced Toxicity +11

Age-related alteration in the distribution of methylglyoxal and its metabolic enzymes in the mouse brain

Shin Koike, Chihiro Ando, Yosuke Usui et al. · Brain Research Bulletin · 2018 · 27 citations

Aging, Lipid Peroxidation, Physiology +8

Nrf2 activation ameliorates cytotoxic effects of arsenic trioxide in acute promyelocytic leukemia cells through increased glutathione levels and arsenic efflux from cells

Shoichi Nishimoto, Toshihiro Suzuki, Shin Koike et al. · Toxicology and Applied Pharmacology · 2016 · 22 citations

Reductive Stress, Medicine, Lipid Peroxidation +10