Ján Jakubík

Positive Cooperativity of Acetylcholine and Other Agonists with Allosteric Ligands on Muscarinic Acetylcholine Receptors

Ján Jakubík, Lucie Bačáková, Esam E. El‐Fakahany et al. · Molecular Pharmacology · 1997 · 229 citations

Activation of muscarinic acetylcholine receptors via their allosteric binding sites.

Ján Jakubík, Lucie Bačáková, Esam E. El‐Fakahany et al. · Proceedings of the National Academy of Sciences · 1996 · 112 citations · Full text

Molecular Pharmacology, Signal Transduction, Biochemistry +14

Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors.

Ján Jakubík, Lucie Bačáková, Esam E. El‐Fakahany et al. · Journal of Pharmacology and Experimental Therapeutics · 1995 · 74 citations

Constitutive activity of the M₁–M₄ subtypes of muscarinic receptors in transfected CHO cells and of muscarinic receptors in the heart cells revealed by negative antagonists

Ján Jakubík, Lucie Bačáková, Esam E. El‐Fakahany et al. · FEBS Letters · 1995 · 74 citations

Synaptic Transmission, Cellular Pharmacology, Heart Cells +18

Differences in Kinetics of Xanomeline Binding and Selectivity of Activation of G Proteins at M1 and M2 Muscarinic Acetylcholine Receptors

Ján Jakubík, Esam E. El‐Fakahany, Vladimı́r Doležal · Molecular Pharmacology · 2006 · 53 citations