Michael J. Harms

Protein Evolution by Molecular Tinkering: Diversification of the Nuclear Receptor Superfamily from a Ligand-Dependent Ancestor

Jamie T. Bridgham, Geeta N. Eick, Claire Larroux et al. · PLoS Biology · 2010 · 251 citations · Full text

Genetics, Molecular Tinkering, Molecular Biology +20

Arginine residues at internal positions in a protein are always charged

Michael J. Harms, J.L. Schlessman, Gloria R. Sue et al. · Proceedings of the National Academy of Sciences · 2011 · 184 citations · Full text

Protein Assembly, Molecular Biology, Protein Synthesis +16

Detecting High-Order Epistasis in Nonlinear Genotype-Phenotype Maps

Zachary R. Sailer, Michael J. Harms · Genetics · 2017 · 175 citations · Full text

Genetics, Epistasis, Genetic Analysis +16

Historical contingency and its biophysical basis in glucocorticoid receptor evolution

Michael J. Harms, Joseph W. Thornton · Nature · 2014 · 158 citations · Full text

Historical Contingency, Behavioral Neuroscience, Functional Selectivity +11

The pKa Values of Acidic and Basic Residues Buried at the Same Internal Location in a Protein Are Governed by Different Factors

Michael J. Harms, Carlos A. Castañeda, J.L. Schlessman et al. · Journal of Molecular Biology · 2009 · 153 citations

Protein Chemistry, Basic Residues Buried, Protein Function +12