Regulation of γδ Versus αß T Lymphocyte Differentiation by the Transcription Factor SOX13

Heather J. Melichar, Kavitha Narayan, Sandy D. Der, +6

Science

Lymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellImmune RegulationImmunology +17

A Network of High-Mobility Group Box Transcription Factors Programs Innate Interleukin-17 Production

Kavitha Narayan, Ok Hyun Cho, Katelyn Sylvia, +7

Immunity

InflammationCytokineAutoimmune DiseaseInnate Immune SystemGene Expression +7

Increased Production of Interleukin-8 in Primary Human Monocytes and in Human Epithelial and Endothelial Cell Lines after Dengue Virus Challenge

Irene Bosch, Kris Xhaja, Luis Estevez, +6

Journal of Virology

Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation

Masayuki Hata, Elisabeth M. M. A. Andriessen, Maki Hata, +17

Science

Innate Immune SystemImmunologyCell DeathAge-related Macular DegenerationInnate Immunity +20

Distinct Temporal Patterns of T Cell Receptor Signaling During Positive Versus Negative Selection in Situ

Heather J. Melichar, Jenny O. Ross, Paul Herzmark, +2

Science Signaling

Lymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellImmunologyRegulatory T Cells +17

Interleukin-17-Producing γδ T Cells Originate from SOX13+ Progenitors that Are Independent of γδTCR Signaling

Nicholas A. Spidale, Katelyn Sylvia, Kavitha Narayan, +12

Immunity

Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development

Byron B. Au‐Yeung, Heather J. Melichar, Jenny O. Ross, +5

Nature Immunology

Temporal RequirementsT Cell DevelopmentSignal TransductionBiochemistryMedicine +8

Opposing chemokine gradients control human thymocyte migration in situ

Joanna Halkias, Heather J. Melichar, Kayleigh T. Taylor, +5

Journal of Clinical Investigation

Lymphocyte DevelopmentT-regulatory CellImmunologyImmune RegulationHuman Thymocytes +16

Distinct phases in the positive selection of CD8⁺T cells distinguished by intrathymic migration and T-cell receptor signaling patterns

Jenny O. Ross, Heather J. Melichar, Byron B. Au‐Yeung, +3

Proceedings of the National Academy of Sciences

Basal Intracellular CalciumLymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellImmune Regulation +20

Conserved and divergent aspects of human T‐cell development and migration in humanized mice

Joanna Halkias, Bonnie Yen, Kayleigh T. Taylor, +4

Immunology and Cell Biology