Impaired Prion Replication in Spleens of Mice Lacking Functional Follicular Dendritic Cells

Fabio Montrasio, Rico Frigg, Markus Glatzel, +4

Science

InflammationMature FdcsAutoimmune DiseaseGranulocyteImmune Cell Development +13

Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models

Andreas Weihofen, Yuting Liu, Joseph W. Arndt, +16

Neurobiology of Disease

Disease ModelsNeurodegenerative Diseasesα-Syn PathologyAutoimmune DiseaseDisease Phenotypes +13

Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells

Marco Prinz, Fabio Montrasio, Michael A. Klein, +5

Proceedings of the National Academy of Sciences

Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro

Chloe K. Nobuhara, Sarah L. DeVos, Caitlin Commins, +18

American Journal Of Pathology

Neurodegenerative DiseasesLaboratory ImmunologyInterneuron PropagationMedicineCell Trafficking +7

Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model

Lien Nguyen, Fabio Montrasio, Amrutha Pattamatta, +19

Neuron

Neurodegenerative DiseasesAmyotrophic Lateral SclerosisAutoimmune DiseaseImmunologyAntibody Engineering +3

Abnormal synaptic protein expression and cell death in murine scrapie

S. Sis x F, Berta Puig, Ruth Varea, +8

Acta Neuropathologica

Protein FunctionMolecular NeuroscienceSignal TransductionMedicineApoptosis +10

A human-derived antibody targets misfolded SOD1 and ameliorates motor symptoms in mouse models of amyotrophic lateral sclerosis

Marcel Maier, Tobias Welt, Fabian Wirth, +12

Science Translational Medicine

B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice

Fabio Montrasio, Antonio Cozzio, Eckhard Flechsig, +8

Proceedings of the National Academy of Sciences

Enable Prion ReplicationKnockout MouseAutoimmune DiseaseImmune Cell DevelopmentMedicine +12

Circumventing Tolerance to the Prion Protein (PrP): Vaccination with PrP-Displaying Retrovirus Particles Induces Humoral Immune Responses against the Native Form of Cellular PrP

Daphne Nikles, Patricia Bach, Klaus Böller, +7

Journal of Virology

Lymphotoxin-β Receptor-Dependent Genes in Lymph Node and Follicular Dendritic Cell Transcriptomes

Christoph Huber, Caroline Thielen, Harald Seeger, +7

The Journal of Immunology