Zachary S. Clayton

Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans

Vienna E. Brunt, Abigail G. Casso, Rachel A. Gioscia‐Ryan et al. · Hypertension · 2021 · 95 citations · Full text

Life Sciences, Cardiology, Microbiology +17

Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence

Sophia Mahoney, Ravinandan Venkatasubramanian, Mary A. Darrah et al. · Aging Cell · 2023 · 89 citations · Full text

Education, Pharmacology, Physiology +17

Cellular Senescence Contributes to Large Elastic Artery Stiffening and Endothelial Dysfunction With Aging: Amelioration With Senolytic Treatment

Zachary S. Clayton, Matthew J. Rossman, Sophia Mahoney et al. · Hypertension · 2023 · 84 citations · Full text

Education, Cardiology, Physiology +15

Doxorubicin-Induced Oxidative Stress and Endothelial Dysfunction in Conduit Arteries Is Prevented by Mitochondrial-Specific Antioxidant Treatment

Zachary S. Clayton, Vienna E. Brunt, David A. Hutton et al. · JACC CardioOncology · 2020 · 72 citations · Full text

Life Sciences, Cardiology, Pharmacology +17

Heat therapy improves glucose tolerance and adipose tissue insulin signaling in polycystic ovary syndrome

Brett R. Ely, Zachary S. Clayton, Carrie E. McCurdy et al. · American Journal of Physiology-Endocrinology and Metabolism · 2019 · 70 citations · Full text

Medicine, Endocrinology, Gynecology +17