Cassandra L. Ramage

Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

Qi Zhang, Bridget Riley‐Gillis, Lina Han et al. · Signal Transduction and Targeted Therapy · 2022 · 168 citations · Full text

Co-targeting BCL-XL and BCL-2 by PROTAC 753B eliminates leukemia cells and enhances efficacy of chemotherapy by targeting senescent cells

Yannan Jia, Lina Han, Cassandra L. Ramage et al. · Haematologica · 2023 · 52 citations · Full text

Cancer Targets, Different Leukemia Subsets, Immunology +17

Combined Blockade of CD47-Sirpa Interaction By 5F9 (Magrolimab) and Azacitidine/Venetoclax Therapy Facilitates Macrophage-Mediated Anti-Leukemia Efficacy in AML Pre-Clinical Models

Yannan Jia, Qi Zhang, Connie C. Weng et al. · Blood · 2021 · 21 citations

Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis in vitro

Katie Hege-Hurrish, Yongwei Su, Shraddha Patel et al. · Biochemical Pharmacology · 2023 · 18 citations · Full text

Inflammation, Anti-inflammatory, Medicine +6

Transcriptional and phenotypic heterogeneity underpinning venetoclax resistance in AML

Vakul Mohanty, Natalia Baran, Yuefan Huang et al. · 2024 · 10 citations · Full text