Kathrin Eberhardt

Defining the clinical, molecular and imaging spectrum of adaptor protein complex 4-associated hereditary spastic paraplegia

Darius Ebrahimi‐Fakhari, Julian Teinert, Robert Behne et al. · Brain · 2019 · 74 citations · Full text

Adaptor protein complex 4 deficiency: a paradigm of childhood-onset hereditary spastic paraplegia caused by defective protein trafficking

Robert Behne, Julian Teinert, Miriam Wimmer et al. · Human Molecular Genetics · 2019 · 73 citations · Full text

Genetics, Ap-4 Subunits, Molecular Biology +18

Macrophage cultures are susceptible to lytic productive infection by endothelial-cell-propagated human cytomegalovirus strains and present viral IE1 protein to CD4+ T cells despite late downregulation of MHC class II molecules

Christian Sinzger, Kathrin Eberhardt, Yolaine Cavignac et al. · Journal of General Virology · 2006 · 47 citations

Intrathecal AAV9/AP4M1 gene therapy for hereditary spastic paraplegia 50 shows safety and efficacy in preclinical studies

Xin Chen, Thomas Dong, Yuhui Hu et al. · Journal of Clinical Investigation · 2023 · 43 citations · Full text

Pain Disorders, Viral Pathogenesis, Pathology +17

High-throughput imaging of ATG9A distribution as a diagnostic functional assay for adaptor protein complex 4-associated hereditary spastic paraplegia

Darius Ebrahimi‐Fakhari, Julian E. Alecu, Barbara Brechmann et al. · Brain Communications · 2021 · 19 citations · Full text