Eric J. Downer

CD200 Ligand–Receptor Interaction Modulates Microglial Activation<i>In Vivo</i>and<i>In Vitro</i>: A Role for IL-4

Anthony Lyons, Eric J. Downer, S Crotty et al. · Journal of Neuroscience · 2007 · 259 citations · Full text

Immunology, Immune Regulation, Cd4 T Cell Responses +19

Fractalkine‐induced activation of the phosphatidylinositol‐3 kinase pathway attentuates microglial activation <i>in vivo</i> and <i>in vitro</i>

Anthony Lyons, Aileen Lynch, Eric J. Downer et al. · Journal of Neurochemistry · 2009 · 196 citations · Full text

Fractalkine Expression, Cellular Physiology, Neuroinflammation +20

The polyunsaturated fatty acids, EPA and DPA exert a protective effect in the hippocampus of the aged rat

Laura Kelly, Belinda Grehan, Andrea Della Chiesa et al. · Neurobiology of Aging · 2010 · 134 citations

Aging, Omega-3 Fatty Acid, Physiology +6

Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide

Anthony Lyons, Keith McQuillan, Brian F. Deighan et al. · Brain Behavior and Immunity · 2009 · 97 citations

Inflammation, Increased Neuroinflammation, Cytokine +12

Δ9-Tetrahydrocannabinol induces the apoptotic pathway in cultured cortical neurones via activation of the CB1 receptor

Eric J. Downer, Barry Boland, Marie P. Fogarty et al. · Neuroreport · 2001 · 90 citations

Apoptotic Pathway, Cannabinoid Pharmacology, Synaptic Signaling +20